The Gottwaldov II route is dedicated to residential buildings that were built between 1948 and 1989. It complements the existing Gottwaldov I route focused on public and representative buildings from the same period. After a successful two-year economic plan, from which, for example, three-story houses in Obeciny by Vladimír Karfík and the Morýs houses and tower houses by Miroslav Drofa in the eastern part of the city originate, the next stage is characterised by many differences. These are mainly due to the nationalisation of the construction industry and the creation of Stavoprojekt institutes, which were led by the architect Karel Janů, and also the former Baťa architect Jiří Voženílek. One of his major architectural realisations is the Collective House built in the city centre on the grounds of Jan Antonín Bata's villa. In 1951, the first typification proceedings were published by the Study and Typification Institute (Studijní a typizační ústav). The house T13/52 on the corner of třída Tomáše Bati and Lorencova Street, is based on the type published in the proceedings, however, due to the adaptation of the building to the site, it is slightly deviates from the model type. Experimental projects of prefab houses also date from the late 1950s. One of the most successful is a residential building on Stalinova třída (today třída Tomáše Bati), which was part of the Družba cultural complex. Large-capacity buildings built for the employees of local companies form a separate chapter. An example is the apartment house for women (House for Single Mothers), which the national enterprise Svit had built for single women, mothers and widows in the Nad Ovčírnou district in order to solve their poor housing situation. The large-capacity apartment house on Vodní Street is a product of the 1960s era, designed by architect Jan Palacký.
The route will gradually be supplemented with new buildings and urban units.